Treatment of respiratory depression with the anticholinesterase drug galanthamine hydrobromide
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چکیده
منابع مشابه
Nivalin (galanthamine hydrobromide), an additional decurarizing agent. Some introductory observations.
Galanthamine hydrobromide (Nivalin), an alkaloid from the bulbs of snowdrops, is widely used in Bulgaria as an antagonist to non-depolarizing muscle relaxants. The pharmacology is reviewed and experiences in the use of galanthamine in 24 patients are described. It is about one-tenth as potent as neostigmine. As changes in pulse rate and blood pressure were slight, it is rarely necessary to inje...
متن کاملHigh-performance liquid chromatographic determination of galanthamine, a long-acting anticholinesterase drug, in serum, urine and bile.
The anticholinesterase drug galanthamine is obtained from alkalinized serum by repeated liquid--liquid extraction. The resulting extract is approximately 100 times concentrated with respect to the original sample. Quantitative determination of galanthamine is performed with normal-phase liquid chromatography using a mixture of dichloromethane--n-hexane and ethanolamine as an eluent. Phenacetin ...
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Stability-indicating study of the anti-Alzheimer's drug galantamine hydrobromide.
Galantamine hydrobromide was subjected to different stress conditions (acidic, alkaline, thermal, photolytic and oxidative). Degradation was found to occur under acidic, photolytic and oxidative conditions, while the drug was stable under alkaline and elevated temperature conditions. A stability-indicating reversed-phase liquid chromatographic method was developed for the determination of the d...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 1974
ISSN: 0003-2409
DOI: 10.1111/j.1365-2044.1974.tb00722.x